Itching for Relief – The Ins and Outs of Prurigo Nodularis
Prurigo nodularis, or PN, is a skin disease that causes hard bumps, or nodules to form on the skin. These nodules are extremely itchy and can itch constantly. Many people scratch themselves to the point of pain or even bleeding due to the intense itch. Unfortunately, itching the bumps can cause more of them to appear, escalating the vicious cycle.

What causes prurigo nodularis?
While the exact cause of PN is unknown, certain risk factors may make you more prone to developing PN. Some of these include:
- A history of skin conditions that cause itching, such as eczema
- Reduced liver and kidney function
- Type 2 diabetes
- HIV/immunodeficiency
- Some psychological conditions
What exactly do the nodules look like?
The nodules can vary in size. You may have some that are very small and some that are rather large. They typically have a dry, rough top and typically appear on areas like the arms, shoulders, and legs. You may notice a few nodules, or a few hundred.
Is prurigo nodularis genetic?
Prurigo nodularis is not believed to be an inherited disease. If one of your parents has PN, this does not mean that you will develop it. However, since the development of PN is sometimes associated with having other health problems or skin diseases, you may notice a family history associated with those skin conditions.

How is prurigo nodularis treated?
While some treatments to reduce itchiness are available, they don’t work for everyone. Many people with PN may have to try several different treatments without receiving much relief due to the intense itch that comes with PN. Fortunately, if you have prurigo nodularis, you may be eligible for currently enrolling research studies to help find potential new PN treatment options.
Physicians at ActivMed Practices & Research, INC are seeking adults with PN for local enrolling research studies. Qualified candidates who participate will receive study-related care at no cost and receive compensation for travel. CLICK HERE to learn more and see if you or a loved one may qualify for studies enrolling in Beverly, MA or CLICK HERE to learn more about PN studies enrolling in Portsmouth, NH.
- Blog (139)
- Alzheimer's Disease (18)
- Atopic Dermatitis (4)
- Alzheimers Clinical Trials (2)
- Charity Event (2)
- Chronic Conditions (2)
- #CTD2020 (1)
- 2019 (1)
- Acne (1)
- Adolescent (1)
- Advice (1)
- Age Friendly (1)
- Alzheimer's Agitation (1)
- Alzheimer's Research (1)
- Alzheimer's and Brain Awareness Month (1)
- Alzheimers Study (1)
- American Heart Association (1)
- American Heart Month (1)
- American Stroke Month (1)
- Annual (1)
- Article (1)
- Atopic Dermatitis Care (1)
- Baseline Memory Screen (1)
- Binge Eating (1)
- Blood Pressure (1)
- Brain Health (1)
- Caregiver (1)
- Chronic Pain (1)
- April 2022 (2)
- March 2022 (2)
- February 2022 (2)
- January 2022 (2)
- December 2021 (2)
- November 2021 (2)
- October 2021 (2)
- September 2021 (2)
- August 2021 (3)
- July 2021 (2)
- June 2021 (1)
- May 2021 (1)
- April 2021 (2)
- March 2021 (2)
- February 2021 (3)
- January 2021 (2)
- December 2020 (2)
- November 2020 (3)
- October 2020 (2)
- September 2020 (3)
- August 2020 (4)
- July 2020 (3)
- June 2020 (3)
- May 2020 (5)
- April 2020 (2)
- March 2020 (6)
- February 2020 (2)
- January 2020 (4)
- December 2019 (3)
- November 2019 (5)
- October 2019 (8)
- September 2019 (3)
- August 2019 (3)
- July 2019 (3)
- June 2019 (5)
- May 2019 (6)
- April 2019 (5)
- March 2019 (3)
- February 2019 (2)
- January 2019 (2)
- December 2018 (4)
- November 2018 (3)
- October 2018 (5)
- September 2018 (5)
- August 2018 (8)
- July 2018 (6)
- June 2018 (5)
- May 2018 (4)
- April 2018 (6)
- March 2018 (4)
- February 2018 (1)
- January 2018 (2)
- December 2017 (2)
- November 2017 (4)
- October 2017 (1)
- September 2017 (1)
- August 2017 (2)
- July 2017 (1)
- May 2017 (2)
- April 2017 (2)
- March 2017 (4)
- September 2016 (2)
- August 2016 (3)
- July 2016 (1)
- May 2016 (2)
- April 2016 (1)
- March 2016 (1)
- February 2016 (1)
- January 2016 (3)
- October 2014 (1)
